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Why isn't an SAPGUI re-installation correcting a user's blank workflow?

A user has a new PC with Windows 2000 as the operating system and SAPGUI 4.6D. When they go to transaction ME52, ME53 or the Business Workplace, the workflow area is blank. My understanding is that Microsoft and SAP have similar security patch files, and if they are not installed in the correct order on a new PC, this blank workflow issue occurs. We reinstalled the SAPGUI, and it has solved this issue in the past. Now we have tried reinstalling the SAPGUI for this user, and it has not corrected the blank workflow issue. I have done research with OSS notes have not found any other solution than to reinstall the SAPGUI. Do you have any insight on what we can try next and why this is happening?
I would upgrade the user to a newer SAPGUI release, such as 6.20 compilation 6 or SAPGUI 6.40 compilation 3. If the new SAPGUI works fine I would also consider putting it on everybody else's computers and have a uniform environment.

As for what can be causing the problem, it could be many things, really, and it's very difficult to pinpoint it without trying some things.

SAP note 214601 is a good example of problems with SAPGUI misbehaving. Also, do not use SAPGUI 6.20 with patch level 40. See SAP note 738099.

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