When the transaction support NAST messaging, customize a new output message for ALE that is created with the document. This poutput message the sends out ALEAUD etc. (in case of PO, better send the ORDERS03 as aorder acknowledgement.)
A detailed explaination of how this can be accomplished is part the following IBM Redbook:
Lee Gavin, Axel Angeli
A B2B Solution using WebSphere Business Integration V4.1 and WebSphere Business Connection V1.1
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